Specialized organoid-based assays for modeling human biology in vitro—designed to enhance predictive accuracy in drug response, toxicity, and disease progression.
As a company specialized in organoids, we provide high-quality, customized solutions and support a differentiated one-stop service from production to delivery and post-management.
hCRC organoids exhibit a three-dimensional structure and cellular composition similar to colorectal cancer tissue.
They express proteins such as CK7, CK20, b-catenin, and CDX2, mirroring the characteristics of colorectal cancer tissue.
These organoids are highly valuable for analyzing genetic mutations in colorectal cancer and evaluating the efficacy of different chemotherapy treatments.
Lung cancer (NSCLC, Non-small cell lung cancer) organoids are three-dimensional (3D) models that closely replicate the structure and cellular composition of actual cancer tissue.
By preserving key characteristics of NSCLC, including genetic mutations and protein expression patterns, these organoids serve as reliable models for cancer research.
Their ability to maintain tumor heterogeneity and accurately mimic the tumor microenvironment (TME) makes them invaluable for studying disease progression and treatment responses.
As physiologically relevant models, NSCLC organoids play a crucial role in advancing precision medicine and facilitating the development of more effective cancer therapies.
Enhanced Tumor Mimicry â–¶ Integrate CAFs with organoids to recreate the tumor microenvironment accurately, providing a realistic platform for oncology research.
Improved Drug Response Insight â–¶ By simulating the complex interactions within the tumor microenvironment, our CAF-enhanced organoids offer deeper insights into drug efficacy and resistance mechanisms.
Accelerated Cancer Research â–¶ Leverage the dynamic interaction between CAFs and tumor cells in our organoids to speed up the discovery of novel therapeutic targets and improve treatment strategies.
A co-culturing platform of macrophages and organoids demonstrates varying organoid cytotoxic effects depending on the ratio of M1 macrophages to M2 macrophages.
Optimal cell death effects are established by co-culturing different ratios of functionally diverse immune cells.
This enables the identification of optimal conditions for co-culturing various immune cells, facilitating the selection of an appropriate platform for drug testing.
Tumor-Infiltrating Lymphocytes (TILs) are predominantly found in the microenvironment of tumors, including various types of lymphocytes that have infiltrated in and around tumor tissues.
Among them, CD8+ cytotoxic T cells and CD4+ helper T cells are major components.
Our approach involves isolating and expanding TILs from a patient’s tumor tissue, then evaluating the efficacy of anticancer agents in a tumor microenvironment containing cancer organoids and TILs.
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