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Organism | |
Product Type | Organoid |
Tissue | iPSC |
Disease |
Applications
Retinal diseases (such as macular degeneration)
Inflammatory Bowel Disease (IBD) refers to a chronic condition characterized by inflammation within the gastrointestinal tract, causing inflammation of the intestinal walls.
Drug efficacy and toxicity for treatment
Lambda's Intestinal Fibrosis Model addresses these challenges by leveraging high mimetic human intestinal organoids to create a model of inflammatory bowel diseases.
We successfully developed retinal organoids from human pluripotent stem cells (hPSCs) using advanced differentiation technology.
The human retina can be broadlydivided into the Neural Retina and Retinal Pigmented Epithelium. We confirmed the expression of specific markers present in each layer of the retina in theretinal organoids. Around 25 days of cultivation, the presence of Retinal Ganglion Cells and Bipolar Cell layers was observed, along with the expression of the specific marker Paired Box Protein-6 (Pax6). Furthermore, by observing changes in cell arrangement within the organoid andexamining the marker for photosensitive cells (Recoverin), we confirmed thesimilarity of the produced retinal organoid to human tissue.
@ 2024 . All rights reserved
@ 2024 . All rights reserved