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Normal Organoid

Retinal Organoid

4350€+
Normal Organoid

Retinal Organoid

  • Retinal organoids replicate the diverse cell types found in the human retina, allowing for detailed studies of retinal development and function.
    Retinal organoids replicate human retina for detailed developmental studies.
  • They serve as models for studying retinal diseases like retinitis pigmentosa and age-related macular degeneration, aiding in disease understanding and therapeutic development.
    Models for retinal diseases aid understanding and therapy development.
  • Retinal organoids are used to screen potential drugs for retinal disorders, providing a platform to assess drug efficacy and safety in a controlled experimental environment.
    Screen drugs for retinal disorders' efficacy and safety accurately.

Price
Organism
Human
Product Type
Organoid
Tissue
iPSC
Disease

Applications

Toxicity

Organoid Based

Professor Lee Chang-seok Eulji University
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Description

Table of Contents

Establishment of retinal organoid differentiation

We successfully developed retinal organoids from human pluripotent stem cells (hPSCs) using advanced differentiation technology.

Cellular and structural similarity

Retinal organoid structure

The human retina can be broadlydivided into the Neural Retina and Retinal Pigmented Epithelium.
We confirmed the expression of specific markers present in each layer of the retina in theretinal organoids.
Around 25 days of cultivation, the presence of Retinal Ganglion Cells and Bipolar Cell layers was observed, along with the expression of the specific marker Paired Box Protein-6 (Pax6).
Furthermore, by observing changes in cell arrangement within the organoid andexamining the marker for photosensitive cells (Recoverin),
we confirmed thesimilarity of the produced retinal organoid to human tissue.

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