2024: research in review
Journal: Nature Biotechnology
A review of 2024’s significant biotechnological advancements, highlighting key research breakthroughs.
The article provides an overview of notable biotechnological developments in 2024, including the creation of glucose-responsive insulin, advancements in MHC I-binding systems for targeted peptide antigens, and innovations in optical perturbation screening methods.
Integrating bioelectronics with cell-based synthetic biology
Journal: Nature Reviews Bioengineering
Author: Jonathan Rivnay et. al , USA
Review explores synergy between engineered cells and bioelectronics for next-generation therapeutic applications.
Comprehensive review of cell-bioelectronics integration highlighting potential for regulated cell therapies and diagnostics, emphasizing closed-loop control systems and biohybrid devices.
Intratumor heterogeneity of EGFR expression
Journal: Nature Communications
Author: Bassel Alsaed et. al, Finland
Study reveals how EGFR expression variation influences drug resistance in lung cancer.
Research identifies how low-EGFR expressing cancer cells contribute to drug resistance and tumor microenvironment modification, suggesting new combination therapy approaches.
Endothelial-secreted Endocan activates PDGFRA
Journal: Nature Communications
Author: Soniya Bastola et al., USA
Study reveals Endocan’s role in glioblastoma progression through PDGFRA activation.
Investigation shows how endothelial-secreted Endocan influences glioblastoma behavior through PDGFRA signaling, affecting tumor growth and treatment resistance.
