Collagen Supplementation for Skin and Musculoskeletal Health: An Umbrella Review of Meta-Analyses on Elasticity, Hydration, and Structural Outcomes
Journal: Aesthetic Surgery Journal Open Forum
Author: Roshan Ravindran et al., UK
A massive review of collagen research found that the supplements can improve skin elasticity and hydration while helping reduce osteoarthritis pain and stiffness
Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse
Journal: Cell Journal
Author: Gattinoni L, Inchingolo G, Harrer D et al., Germany
A first-in-human study shows donor-derived CAR TSCM cells achieve durable responses, superior persistence, and stem-cell compartment renewal, highlighting their potential as next-generation CAR-T therapies.
A 3D morphogenetic blueprint for metastatic outgrowth in breast cancer
Journal: Cell Journal
Author: Robin Caire et al., Italy
Researchers uncovered a developmental branching morphogenesis program that drives breast cancer metastatic outgrowth, revealing ETV1/4/5 and FGF-FGFR signaling as promising therapeutic targets specific to lethal macrometastases.
Efficacy, safety, and biomarker analysis of datopotamab deruxtecan in advanced non-small cell lung cancer: ICARUS-LUNG01 phase 2 study
Journal: Cancer Cell
Author: David Planchard et al., France
The phase II ICARUS-LUNG01 study demonstrates the efficacy of datopotamab deruxtecan in advanced NSCLC and identifies potential biomarkers that may predict treatment response and resistance.
