TECH FEST

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Advanced Co-culture Systems: Enhancing Cancer Research with Organoid-immune Models

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🫁NF-κB Inhibitor Alpha Controls SARS-CoV-2 Infection in ACE2-Overexpressing Human Airway Organoids

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Intestinal Organoids to Model Salmonella Infection and Its Impact on Progenitors!

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Utilizing Human Cerebral Organoids to Model Breast Cancer Brain Metastasis in Culture

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💧 Lubricant-Coated Organ-on-a-Chip for Enhanced Precision in Preclinical Drug Testing

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A Cell Pre-Wrapping Seeding Technique for Hydrogel-Based Tubular Organ-On-A-Chip

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💾An Ultrathin Membrane Mediates Tissue-Specific Morphogenesis and Barrier Function in a Human Kidney Chip

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Characterization of Patient-Derived Intestinal Organoids for Modelling Fibrosis in Inflammatory Bowel Disease

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Azoxymethane-Induced Carcinogenesis-Like Model of Mouse Intestine and Mouse Embryonic Stem Cell-Derived Intestinal Organoids

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The First Turtle Organoids

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Modeling Blood-Brain Barrier Formation and Cerebral Cavernous Malformations in Human PSC-Derived Organoids

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Efficient Hepatocyte Differentiation of Primary Human Hepatocyte-Derived Organoids Using Three Dimensional Nanofibers (HYDROX) and Their Possible Application in Hepatotoxicity Research

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Designer Immune-cell Therapy Could Shrink Deadly Brain Tumors

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Major AlphaFold Upgrade Offers Boost for Drug Discovery

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First Model of the Brain’s Information Highways Developed

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AI Traces Mysterious Metastatic Cancers to Their Source

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Antibody Therapy Makes the Immune Systems of Old Mice Young Again

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Heterozygous RB1 Mutation Enhanced ATP Production in Human iPSC-Derived Retinal Organoids

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Synergistic Hyperactivation of Both mTORC1 and mTORC2 Underlies the Neural Abnormalities of PTEN-deficient Human Neurons and Cortical Organoids

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Hyaluronan Improves Photoreceptor Differentiation and Maturation in Human Retinal Organoids

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High-Fat Diet Enhances Cell Proliferation and Compromises Intestinal Permeability in a Translational Canine Intestinal Organoid Model

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Organoids as Advanced Model in Cancer Biology: The Drug Screening and Clinical Applications

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Pioneering Technologies Transforming Drug Discovery: From Preclinical Assessments to Clinical Trials

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Organoids: Today’s Research Tool, Tomorrow’s Organ Transplant Solution

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Newly Developed Organoid Model Can be Used to Study Thymus Function

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Scientists Discover New Phage Resistance Mechanism in Phage-bacterial Arms Race

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AI Tool Creates ‘Synthetic’ Images of Cells for Enhanced Microscopy Analysis

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Liquid Droplets Shape How Cells Respond to Change

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Vitamin D Opposes Multilineage Cell Differentiation Induced by Notch Inhibition and BMP4 Pathway Activation in Human Colon Organoids

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Endogenous Mutant Huntingtin Alters the Corticogenesis via Lowering Golgi Recruiting ARF1 in Cortical Organoid

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Claudin-7 Is Essential for the Maintenance of Colonic Stem Cell Homoeostasis via the Modulation of Wnt/Notch Signaling

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FGF7 Enhances the Expression of ACE2 in Human Islet Organoids Aggravating SARS-CoV-2 Infection

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Replacing Animal Testing with Stem Cell-Organoids : Advantages and Limitations

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Establishment, Characterization, and Biobanking of 36 Pancreatic Cancer Organoids: Prediction of Metastasis in Resectable Pancreatic Cancer

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A Pancreatic Cancer Organoid-in-Matrix Platform Shows Distinct Sensitivities to T Cell Killing

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Antisense Oligonucleotide Therapeutic Approach for Timothy Syndrome

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Spatiotemporally Resolved Colorectal Oncogenesis in Mini-Colons Ex Vivo

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A Patient-specific Lung Cancer Assembloid Model with Heterogeneous Tumor Microenvironments

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Mini-colon and Brain ‘Organoids’ Shed Light on Cancer and Other Diseases

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Found: The Dial in the Brain that Controls the Immune System

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UTIs Make Life Miserable — Scientists Are Finding New Ways to Tackle Them

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First Fetus-to-fetus Transplant Demonstrated in Rats

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Do Cutting-edge CAR-T-cell Therapies Cause Cancer? What the Data Says

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‘ChatGPT for CRISPR’ Creates New Gene-editing Tools

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Rat Neurons Repair Mouse Brains — And Restore Sense of Smell

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How to Supercharge Cancer-fighting Cells: Give Them Stem-cell Skills

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mRNA Drug Offers Hope for Treating a Devastating Childhood Disease

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Diabetes Drug Slows Development of Parkinson’s Disease

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Right- or Left-handed? Protein in Embryo Cells Might Help Decide

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Gut Bacteria Break Down Cholesterol — Hinting at Probiotic Treatments

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Scientists Made a Six-legged Mouse Embryo — Here’s Why

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Memories Are Made By Breaking DNA — And Fixing It

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First Pig Kidney Transplant in a Person: What it Means for the Future

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Quantifying Y Chromosome Loss in Primary and Metastatic Prostate Cancer by Chromosome Painting

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Identification of Genes that Promote PI3K Pathway Activation and Prostate Tumour Formation

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In Utero and Postnatal Ivacaftor/Lumacaftor Therapy Rescues Multiorgan Disease in CFTR-F508del Ferrets

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SF3B3-regulated mTOR Alternative Splicing Promotes Colorectal Cancer Progression and Metastasis

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Modeling Acute Myocardial Infarction and Cardiac Fibrosis Using Human Induced Pluripotent Stem Cell-Derived Multi-Cellular Heart Organoids

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‘Mini Liver’ Will Grow in Person’s Own Lymph Node in Bold New Trial

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Survival and Functional Integration of Human Embryonic Stem Cell–Derived Retinal Organoids after Shipping and Transplantation into Retinal Degeneration Rats

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Blood Vessel Organoids Generated by Base Editing and Harboring Single Nucleotide Variation in Notch3 Effectively Recapitulate CADASIL-Related Pathogenesis

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High-Dose Short-Term Osimertinib Treatment Is Effective in Patient-Derived Metastatic Colorectal Cancer Organoids

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SARS-CoV-2 Infection Activates Inflammatory Macrophages in Vascular Immune Organoids

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3D-Printed Tumors Replicate Biopsies of Cancer Patients

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Lifelike Lab-grown Skin Developed from Human Stem Cells

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Organoids Research Identifies Factor Involved in Brain Expansion in Humans

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International Research Team Achieves First-reported, Complete Vascularization of Organoids on Microfluidic Chip

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Establishment of Patient-derived Organoids for Guiding Personalized Therapies in Breast Cancer Patients

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Parechovirus Infection in Human Brain Organoids: Host Innate Inflammatory Response and not Neuro-infectivity Correlates to Neurologic Disease

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ASU Researcher’s Microscale Tech is Chipping Away at Cancer, Organ Failure and Neurological Disease

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Advances and Applications of Cancer Organoids in Drug Screening and Personalized Medicine

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cDC2 Plasticity and Acquisition of a DC3-Like Phenotype Mediated by IL-6 and PGE2 in a Patient-Derived Colorectal Cancer Organoids Model

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MSCs Alleviate LPS-Induced Acute Lung Injury by Inhibiting the Proinflammatory Function of Macrophages in Mouse Lung Organoid-Macrophage Model

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Cholangiocyte Organoids to Study Drug-Induced Injury

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Stem Cells Model of Early Human Central Nervous System Created

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Bioengineering Toolkits for Potentiating Organoid Therapeutics

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Microglial Over-Pruning of Synapses during Development in Autism-Associated SCN2A-Deficient Mice and Human Cerebral Organoids

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Efficient Generation of Skin Organoids from Pluripotent Cells via Defined Extracellular Matrix Cues and Morphogen Gradients in a Spindle-Shaped Microfluidic Device

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Patient Derived Tumoroids of High Grade Neuroendocrine Neoplasms for More Personalized Therapies

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Neuropathogenesis-on-Chips for Neurodegenerative Diseases

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Single-Cell Guided Prenatal Derivation of Primary Fetal Epithelial Organoids from Human Amniotic and Tracheal Fluids

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Neuromuscular Organoids Model Spinal Neuromuscular Pathologies in C9orf72 Amyotrophic Lateral Sclerosis

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Integration of Kupffer Cells into Human iPSC-Derived Liver Organoids for Modeling Liver Dysfunction in Sepsis

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Preclinical Efficacy and Safety of Encapsulated Proliferating Human Hepatocyte Organoids in Treating Liver Failure

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Deciphering Fibroblast-induced Drug Resistance in Non-small Cell Lung Carcinoma Through Patient-derived Organoids in Agarose Microwells

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A Functional Personalised Oncology Approach Against Metastatic Colorectal Cancer in Matched Patient-derived Organoids

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In vitro Neurons Learn and Exhibit Sentience when Embodied in a Simulated Game-world

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A Human Brain Microphysiological System Derived from Induced Pluripotent Stem Cells to Study Neurological Diseases and Toxicity

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Patient-derived Micro-organospheres Enable Clinical Precision Oncology

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Blastocyst-like Structures Generated from Human Pluripotent Stem Cells

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Evolution of Precision Oncology-guided Treatment Paradigms

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Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged Salivary Glands

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Organoid-based Regenerative Medicine for Inflammatory Bowel Disease

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Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations

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Tissue-location-specific transcription programs drive tumor dependencies in colon cancer

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A microfluidic platform integrating functional vascularized organoids-on-chip

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Generation of complex bone marrow organoids from human induced pluripotent stem cells

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Shaping the Neurovascular Unit Exploiting Human Brain Organoids

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Organoid Forming Potential as Complementary Parameter for Accurate Evaluation of Breast Cancer Neoadjuvant Therapeutic Efficacy

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Effective AAV-Mediated Gene Replacement Therapy in Retinal Organoids Modelling AIPL1-Associated LCA4

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Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms

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Mitochondrial network physiology disruption during SARS-CoV-2 infection in human lung organoids

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Rapid Generation of hPSC-Derived High Endothelial Venule Organoids with In Vivo Ectopic Lymphoid Tissue Capabilities

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ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development

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Integrated characterization of hepatobiliary tumor organoids provides a potential landscape of pharmacogenomic interactions

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Mapping the developmental potential of mouse inner ear organoids at single-cell resolution

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Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids

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Urine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation

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Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level

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A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

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Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration

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Waseda researchers unravel secrets of building better brain organoids with blood vessels

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USC Stem Cell scientists develop a game-changing organoid model to study human cerebellar development and disease

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Brain organoids derived from patients taken to space station

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Human Conjunctiva Model Developed For First Time

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Novel model of cortical–meningeal organoid co-culture system improves human cortical brain organoid cytoarchitecture

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Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

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Network-based machine learning in colorectal and bladder organoid models predicts anti-cancer drug efficacy in patients

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Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition

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Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

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Generation of precision preclinical cancer models using regulated in vivo base editing

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One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids

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Middle-out methods for spatiotemporal tissue engineering of organoids

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Methods for Modeling Development

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