The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer’s disease
Journal: PNAS Nexus
Author: Thomas A Shoff et al., USA
A new study from University of California – Riverside suggests Alzheimer’s may start when one protein hijacks another’s job inside brain cells, setting off a cascade of damage.
Expansion and CAR engineering of granulocyte-monocyte progenitors for cellular immunotherapy
Journal: Cell Press Journal
Author: Shi Yue et al., China
Researchers developed a scalable platform for expanding and CAR-engineering granulocyte-monocyte progenitors, enabling durable antitumor immunity and advancing next-generation myeloid cell therapies for cancer.
Self-assembly of tumor-related vascularized colorectal tumoroid-on-a-chip for precision medicine drug testing
Journal: Cell Report Medicine
Author: Zhe Dai et al., China
Researchers developed a vascularized colorectal tumoroid-on-a-chip that better replicates the tumor microenvironment, enabling personalized drug testing and improved evaluation of anti-cancer and anti-angiogenic therapies.
An organoid model of the human adrenal cortex identifies drivers of steroidogenesis and zonation
Journal: Cell Press Blue
Author: Ninouk Akkerman et al., Switzerland
Researchers developed long-lived human adrenal cortex organoids that produce key steroid hormones and reveal molecular pathways governing adrenal zonation, providing a powerful model for adrenal biology and disease research.
