Organoid Library Reveals Mechanisms of Chemotherapy Resistance in Esophageal Cancer Journal: Communications Biology Author: Shunsaku Nakagawa et al., Japan Researchers established a 24-patient esophageal squamous cell carcinoma organoid library that accurately reflects tumor traits. Analysis identified NRF2 pathway activation as key to chemotherapy resistance, even without gene mutations. The study discovered biomarkers for predicting treatment […]