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Top Biotech News (13 Dec 2024)

Gene therapy uptake in sickle cell stays slow, despite patient interest

Summary: A lengthy treatment process, coupled with weighty risks for recipients to consider, has resulted in plodding adoption of Casgevy and Lyfgenia during their first year on market.

A ‘Reverse Aging’ Guru’s Trail of Failed Businesses

Summary: Harvard geneticist David Sinclair aims to develop treatments for aging, but his companies have struggled to deliver

Carisma Therapeutics to Cut 34% of Staff, Reprioritize Pipeline

Summary: Following its second workforce reduction this year, Carisma retains 44 full-time employees while focusing on developing treatments for fibrosis, oncology, and autoimmune diseases.

GSK Touts 42% Survival Benefit for Blenrep in Multiple Myeloma, Strengthening Bid for Market Return

Summary: GSK plans to relaunch Blenrep, previously withdrawn after a failed confirmatory study, leveraging its survival advantage over J&J’s Darzalex.

Pharma giant Sanofi opens $595 million vaccine facility in Singapore to prepare for potential pandemics

Summary: The facility, known as Modulus, can switch between making different vaccines or treatments in a matter of days.

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