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Artificial Skin OECD TG 431

Realistic Skin Structure Similar to Human Skin
This test method uses a reconstructed human epidermis model that mimics the structural and functional properties of actual human skin, providing realistic data. This enables a more accurate prediction of corrosive risks to human skin.
Alternative to Animal Testing
TG 431 was developed as an alternative to animal testing, offering significant ethical benefits. Recognized as a standardized test method by the OECD, it aligns with the global trend of minimizing animal testing, supporting ethical considerations in research.
Standardized Results and High Reproducibility
This test method meets stringent OECD criteria, providing consistent results through standardized procedures. The clearly defined experimental conditions ensure high reproducibility, facilitating data comparison across laboratories and regulatory approval, thus enhancing reliability in regulatory and industry applications.


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Applications

OECD

Skin Corrosion

Description

Artificial Skin OECD TG 431

A human skin model, calledreconstructed human epidermis, is utilized to mimic the biochemical andphysiological characteristics of the human skin surface (epidermis)

Purpose of the test

The test aims to determine if a substance is likely to cause damage to the skin or eyes when exposed to sunlight or other light sources, helping to ensure the safety of chemicals and products such as cosmetics, pharmaceuticals, and industrial substances.

Test Process

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