Breakthrough in Vascularised Organoids
Journal: Cell
Author: Yifei Miao et. al, China
Scientists achieve organotypic vascularisation in lung and intestinal organoids by co-differentiating mesoderm and endoderm, creating functional blood vessels that integrate with host circulation.
Unlocking Mammalian Regeneration
Journal: Science
Author: Weifeng Lin et. al, China
Researchers restore complete ear regeneration in mice by reactivating evolutionarily disabled retinoic acid pathway, offering revolutionary insights for regenerative medicine applications.
Neural Organoids Reveal Viral Pathogenesis
Journal: Nature Communications
Author: Isabel Schultz-Pernice et. al, Switzerland
Human neural organoids demonstrate monkeypox virus susceptibility, showing cell-to-cell spread and neurodegeneration patterns that mirror clinical neurological manifestations observed in patients.
Precision Gene Control Technology
Journal: Nature Communications
Author: Itsuki Abe et. al, Japan
Novel split RNA switches achieve unprecedented specificity in cell-type targeting through protein splicing, advancing mRNA therapeutics with improved safety profiles and reduced off-target effects.