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scRNA Sequence_main
Research Service

scRNA Sequence

scRNA Sequence_main

  • Unmatched Sensitivity
▶ Achieve deep biological insights with reduced sequencing depth and cost.
  • Versatile Analysis
▶ Detect CNVs, profile immune cells, and analyze cell surface proteins at the single-cell level.
  • Reliable and Reproducible
▶ Ensure stable and consistent results across various experiments.

Organism
Human
Product Type
Singe cell RNA sequence
Tissue
Disease

Applications

Singe cell RNA sequence

Single-cell RNA sequencing offers precise individual cell gene expression analysis, overcoming the averaging limitations of bulk RNA sequencing.

Next-Generation Sequencing (NGS)_main
Research Service

Next-Generation Sequencing (NGS)

Next-Generation Sequencing (NGS)_main

  • Precision and Accuracy
▶ We deliver reliable, precise data through state-of-the-art sequencing platforms and rigorous quality control.
  • Customer-Centric Approach
▶ Our services are customized to meet your specific needs, providing personalized support and detailed analyses.
  • Cutting-Edge Bioinformatics Techniques
▶ Utilizing advanced bioinformatics, we offer comprehensive insights through HLA typing, MSI status, mutation rate, and variant concordance.

Organism
Human
Product Type
Next Generation Sequencing(NGS) analaysis services
Tissue
Disease

Applications

Whole Exome Sequencing (WES)

WES provides Whole Exome Sequencing (WES) to comprehensively identify genetic variations, particularly useful for diverse of cells and tissues and especially Organoid Quality Control.

Viral Vector Cloning_main
Research Service

Viral Vector Cloning

Viral Vector Cloning_main

  • Precision in Gene Expression
▶ Our viral vector technology offers precise control over gene expression for over 50 genes, ideal for in vivo nerve cell studies.
  • Versatile Experimental Approaches
▶ Endorsed by top publications, it supports a wide range of experiments, including those using adenovirus, AAV, and lentivirus.
  • Comprehensive Gene Targeting Support
▶ Our Cre On/Off systems and shRNA libraries provide robust support for targeting new genes, enhancing research flexibility and efficiency.

Organism
Human
Product Type
Viral Vector
Tissue
Disease

Applications

Lentivirus

Provides stable, long-term gene expression; ideal for both dividing and non-dividing cells.

AAV (Adeno-Associated Virus)

Offers high precision and low immunogenicity; perfect for targeted gene therapy.

Adenovirus

Delivers high-efficiency gene transfer; suitable for a broad range of cell types and short-term expression.

iPSC Generation_main
Research Service

iPSC Generation

iPSC Generation_main

  • Quality Control and Extensive Experience
▶ With over 1000 iPSC lines generated, we ensure top-quality control through rigorous testing, including RNA reprogramming vector clearance and mycoplasma testing.
  • Rapid Custom Constructs
▶ Quickly obtain stem cell reporter custom constructs with our pipette-free service. Simply email us your gene sequence, and we’ll synthesize and clone it into any of our inducible vectors for minimal cost.
  • Safe and Standardized Reprogramming
▶ Utilizing Sendai virus vectors, we produce transgene-free iPSCs, providing a safer, non-integrating alternative to traditional methods. Our standard package includes the generation of three different iPSC lines per individual and comprehensive pluripotency characterization.

Organism
Human
Product Type
iPSC
Tissue
Kreatinocytes, Urine, Blood, PBMCs
Disease

Applications

iPSC Generation

iPSC lines from patient donor cells ensuring safety and quality through standardized protocols and thorough testing.

iPSC Differentiation

Our iPSC differentiation service offers a comprehensive solution for researchers seeking to explore a diverserange of cell types derived from induced pluripotent stem cells (iPSCs).

Disease Modeling

Utilizing our iPSC technology, we create disease-specific cell models that faithfully mimic human disease conditions.

Drug Discovery

Lambda assists in your drug discovery endeavors by providing a wide range of services, spanning from initial discovery and high-throughput screening to toxicity testing using iPSC-derived cells.

CRISPR-Cas9_main
Research Service

CRISPR-Cas9

CRISPR-Cas9_main

  • Achieve precise and reliable gene editing with our CRISPR-Cas9 technology.
    Enjoy consistent high editing efficiency and stability for your research.
    â–¶ Consistent High Editing Efficiency and Stability
  • Offering expert solutions in cell reprogramming and gene editing, tailored to your needs.
    â–¶ Specialized in Cell Reprogramming
  • IStreamline your workflow and accelerate discoveries by letting us handle the technical challenges. Concentrate on innovation while we support your research
▶ Focus on Your Research

Organism
Human
Product Type
Gene Editing
Tissue
Disease

Applications

Disease Modeling

Create the desired models using diverse patient organoid lines and advanced technology

Fabry’s disease modeling

Inflammatory Bowel Disease (IBD) refers to a chronic condition characterized by inflammation within the gastrointestinal tract, causing inflammation of the intestinal walls.

GeoMx_main
Spatial Biology

GeoMx

GeoMx_main

  • High-Resolution Molecular Analysis
▶ Provides detailed molecular insights through high-resolution imaging combined with RNA and protein analysis.
  • Flexible Targeting
▶ Allows researchers to target specific cell types or tissue regions for simultaneous RNA and protein analysis.
  • Versatile Applications
▶ GeoMx can be extensively used in complex tissue samples for disease research and drug development.

Organism
Human
Product Type
Tissue
Disease

Applications

Visium_main
Spatial Biology

Visium

Visium_main

  • High Resolution
▶ Capture complex tissue structures with Visium's precise gene expression mapping.
  • Comprehensive Insights
▶ Gain detailed insights into cellular interactions and tissue heterogeneity.
  • Broad Applications
▶ Apply Visium across diverse fields like oncology and neuroscience for transformative research.

Organism
Human
Product Type
Tissue
Disease

Applications

OPAL_main
Spatial Biology

OPAL

OPAL_main

  • Precise Spatial Analysis
▶ Access detailed spatial information on slides to analyze cellular composition and intercellular expression networks effectively.
  • Multi-Fluorescent Staining
▶ Utilize our non-barcoding technology for simultaneous scanning with up to seven different fluorescent stains, including DAPI.
  • Cost-Efficient Rapid Detection
▶ Enjoy the benefits of low-cost, marker-focused panels that expedite detection without compromising quality.

Organism
Human
Product Type
Organoid, Tissue
Tissue
Refer to our panel for detailed insights
Disease

Applications

CODEX_main
Spatial Biology

CODEX

CODEX_main

  • Spatial Information Accessibility
▶ Gain insights from detailed spatial information within a slide, allowing for in-depth analysis of cellular composition and the networks of expression factors between cells.
  • Extensive Protein Marker Analysis
▶ Utilize barcoded antibodies to analyze up to 100 protein markers on a single tissue slide, enhancing the depth of your research.
  • Single-Cell Segmentation and Analysis
▶ Achieve precise segmentation and quantitative analysis of expression markers at the single-cell level, providing a high resolution of cellular functionality.

Organism
Human
Product Type
Organoid, Tissue
Tissue
Refer to our panel for detailed insights
Disease

Applications

Melan-A_main
2D Cell

Melan-A

Melan-A_main

  • Targeted Melanin Studies
▶ Utilize the Melan-A cell line to delve into melanin synthesis and regulation, critical for uncovering new pathways to reduce hyperpigmentation and enhance skin brightening.
  • Product Development and Testing
▶ Use Melan-A cells to rigorously test the efficacy of skin brightening agents, ensuring they target and modulate melanin production effectively.
  • Safety and Compatibility Testing
▶ Employ Melan-A cells to assess the safety and skin compatibility of new cosmetic products, making sure they are gentle yet effective for everyday use.

Organism
Product Type
Tissue
Disease

Applications

In vitro 3T3 NR (OECD TG 432)

Comparison of cytotoxicityinduced by chemicals under exposure to non-cytotoxic levels of light versus no exposure to light.