Meet us at ACS FALL 18 - 20 August
ODISEI Organoid-based Discovery Platform Introduction
Home » Latest Research Trends » Latest Research Trends (5 Jun 2025)

Latest Research Trends (5 Jun 2025)

Human Cerebral Organoids Reveal Broader Impact of Angelman Syndrome Gene

Journal: Communications Biology

Author: R. Chris Estridge et. al, USA

Researchers used human cerebral organoids to discover that UBE3A loss affects both neuronal and non-neuronal cells, disrupting brain development beyond neurons and revealing new therapeutic targets.

Gene Editing Safety Concerns as CRISPR Triggers Cellular Senescence in Stem Cells

Journal: Cell Reports Medicine

Author: Anastasia Conti et. al, Italy

CRISPR-Cas9 gene editing unexpectedly induces senescence and inflammation in blood stem cells, reducing their therapeutic potential. Researchers identify treatments to mitigate these adverse effects.

Spatial Biology Breakthrough Maps How Enhancers Control Gene Expression

Journal: Nature Communications

Author: Danni Hong et. al, China

Scientists develop eSpatial technology revealing how different enhancer combinations regulate the same gene across tissue regions, providing new insights into development and cancer heterogeneity.

Miniaturised CRISPR System Shows Promise for Safer Gene Therapy Delivery

Journal: Nature Communications

Author: Shufeng Ma et. al, China

Engineers create hpCasMINI, a compact CRISPR system small enough for viral delivery with enhanced editing efficiency, offering new possibilities for treating genetic diseases in patients.

Subscribe
to the latest updates in the newsletter

Related Solutions

  • Disease Modeling
  • Oncology
  • Organoid
  • Cosmetics
  • OECD TG
  • Zebrafish
  • Bioinfomatics
  • Live&3D Imaging
  • Molecular biology
  • Spatial Biology

Next Articles

Connect with Us