Vascularised Organoids: The Missing Link in Diabetes Research
Journal: Developmental Cell
Author: Yesl Jun et. al, USA
Scientists engineered blood vessels into pancreatic islet organoids, dramatically improving their function and accelerating diabetes reversal in mice—a breakthrough for cell therapy.
Unlocking Heart Regeneration Through Embryonic Signals
Journal: Science Advances
Author: Ning Liu et. al, China
This study identified PTMA protein as a key driver of heart muscle cell proliferation, offering new therapeutic pathways for treating cardiac injury and disease.
Gene Editing Shield: Protecting Therapeutic Cells from Friendly Fire
Journal: Nature Communications
Author: Florence Borot et. al, USA
New base editing technique protects engineered immune cells from their own treatments by removing CD33 markers, improving safety of cell and gene therapies
Small RNA, Big Impact: Discovering Gut Regeneration’s Master
Journal: Science Advances
Author: Jiahang Zhang et. al, China
Scientists found that Snora54 RNA controls intestinal stem cell renewal by regulating Notch2 signalling, revealing new targets for gut repair therapies.