SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
SAVE UPTO 30% ON ORGANOID SERVICES & ASSAYS - Offer end 28 February 2026
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Bridging the Translational Gap

Innovations in Translational Research: Organoids as Versatile Tools for Therapeutic Development

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Abstract

The pharmaceutical landscape is currently undergoing a seismic regulatory shift. With the 2025 joint announcement by the FDA and EMA initiating a phased withdrawal of mandatory animal testing, the race is on for validated,
human-relevant in vitro models. Traditional drug development has long been plagued by exorbitant costs and low success rates due to the physiological discrepancy between animal experiments and human biology.

To address these challenges, ORGANOIDSCIENCES has developed the ODISEI (Organoid-based Discovery platform for Innovative Screening, Evaluation, and Identification) platform—a transformative suite of tools designed to simulate complex human biological interactions with unprecedented accuracy.
The ODISEI platform integrates human organoids with advanced co-culture systems and analytical workflows to provide a credible alternative to conventional 2D assays and animal models.

Authors

R&D Center, Hyunmun Kim1, Boeun Lee1, Seoyeon Kyung2, André Gerth3, Kyung Jin Lee1 3 4, Jongman Yoo1 4

1 ORGANOIDSCIENCES Ltd., Republic of Korea

2 COSMAX BTI, Republic of Korea

3 Lambda Biologics GmbH, Germany

4 Corresponding Author

What you will learn from this research

  • Precision Immuno-Oncology: How co-culturing patient-derived tumor organoids with autologous PBMCs enables real-time visualization of immune activation and personalized therapy testing.
  • New Modality Validation: Strategies for preclinical validation of emerging therapies, including cancer vaccines, mRNA therapeutics, and bispecific antibodies.
  • Dermatological Innovation: The development of hair-bearing organoids that effectively bridge the gap between cell-based assays and clinical hair loss studies.
  • Mechanism-Driven Insights: How to use detailed immunophenotyping to differentiate between drugs with similar clinical outcomes and support indication expansion.
Free downloadable poster

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