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Top Biotech News (07 Feb 2025)

Pfizer Sees Path to Braftovi’s Full Approval With Phase III CRC Data

Summary:

Pfizer’s Braftovi combination therapy shows improved progression-free survival in Phase III BREAKWATER study for colorectal cancer, setting stage for potential full approval in BRAF V600E mutated cases.

Democrats clash with RFK Jr. over vaccine views at heated Senate hearing

Summary:

Health nominee Kennedy faces Senate scrutiny over vaccine positions, pledges pro-safety stance. Democrats challenge past statements while Republican questions focus on abortion, rural healthcare.

Cargo to drop lead CAR-T therapy

Summary:

Cargo Therapeutics halts lead lymphoma cell therapy program after Phase 2 results show high immune reactions and declining remission rates. Company cuts workforce by 50% and shifts focus to early-stage research.

Novartis Eyes More Bolt-On Deals in 2025 as Q4 Earnings Easily Beat Consensus

Summary:

Novartis reports strong Q4 growth with $13.1B in sales, plans to continue aggressive dealmaking after 30 partnerships in 2024. CEO Narasimhan focuses on bolt-on acquisitions for 2030+ growth.

Microbes in space: how bacteria could help sustain long-distance space travel

Summary:

Scientists explore microbes’ diverse roles in space missions, from mining rare-earth metals to making medicines and building materials. ISS experiments show promise, but space microbiology poses unique challenges in microgravity.

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