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Non-Small Cell Lung Cancer Organoid_main
Cancer Organoid

Non-Small Cell Lung Cancer Organoid

1784€+
Cancer Organoid

Non-Small Cell Lung Cancer Organoid

  • These organoids are useful for studying genetic mutations in lung cancer and testing the efficacy of various chemotherapy treatments.
  • They exhibit protein expression patterns of CK5/6, CK7, P40, and TTF-1, allowing for the distinction between different subtypes of lung cancer.
  • hLC organoids replicate the characteristics of lung cancer tissue.
Price
1784€+
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Organism
Human
Product Type
Organoid
Tissue
Lung alveoli, Bronchi
Disease
Non-Small Cell Lung Cancer

Applications

Oncology

Small Molecule

Antibody

Cancer Vaccine

mRNA

Immune Cell

TME-CAF

Immuno Oncology

Macrophage

Regulatory T Cell

Tumor-Infiltrating Lymphocyte

Cytotoxic T Cell

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Description

Table of Contents
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Lung cancer organoid

Our lung cancer organoids accurately replicate patient tumors by expressing key markers TTF-1, CK7, p40 and CK5/6, underscoring their fidelity for cancer research and personalized treatment development.

This molecular mimicry enables a profound understanding of lung cancer pathology and offers a promising avenue for therapeutic innovations.
Lung cancer organoid_01_01
Lung cancer organoid_01_02
Lung cancer organoid
H&E
TTF-1
CK7
p40 (ΔNp63)
CK5/6

Cancer tissue

Adenocarcinoma

Adenosquamous

Cancer organoid

Adenocarcinoma

Adenosquamous

Genetic mutation

Unlock the essence of precision in cancer treatment with our lung cancer organoids, mirroring the  genetic markers of lung cancer. 
Experience the future of testing you drugs, serving as an invaluable tool in capturing the patient-specific characteristics, thereby providing a more accurate platform for studying tumor biology and testing  Dive into a new era of oncology, where your individuality guides our innovation.
Top mutated genes
Lung cancer mutation PPI Network
Genetic analysis in lung cancer organoids

Utilizing a database of protein interactions and mutations, we statistically analyze genetic correlations to identify significant relationships in lung cancer organoids.

Drug response

Embrace personalized medicine with our cutting-edge platform: Test your drug’s effectiveness against conventional treatments under optimal conditions and discover tailored therapeutic responses. Transform the standard with us—where your medication’s potential is as unique as you are.

Cisplatin

Ctr
1μM
3μM
12μM
50μM

Carboplatin

Ctr
1μM
3μM
12μM
50μM

Gemcitabine

Ctr
0.03μM
0.125μM
0.5μM
2μM

Paclitaxel

Ctr
0.25μM
0.5μM
1μM
20μM

Carboplatin

Cisplatin

Gemcitabine

Paclitaxel

Drug responses of patient-derived lung cancer organoids.
Dose-response curves generated from patient-derived lung cancer organoid lines treated with carboplatin, cisplatin, gemcitabine and paclitaxel.
These figures demonstrate the percent of cell viability measured by celltiter-Glo assay.

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Lambda Biologics

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+49 (0) 152 293 76591

info@lambdabiologics.com​

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Germany

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@ 2024 . All rights reserved

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