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2D Cell

Melanocyte

2374€+
2D Cell

Melanocyte

  • Enhanced Pigmentation Studies
    Utilize our melanocyte services to explore pigmentation processes and disorders in-depth, providing crucial insights into skin health and cosmetic development.
  • Tailored Cosmetic Testing
    Assess the efficacy of skincare products on real human melanocytes, ensuring safety and effectiveness tailored to diverse skin types.
  • Advanced Disease Modeling
    Leverage our melanocytes to model skin conditions such as vitiligo and hyperpigmentation, accelerating the discovery of targeted treatments.

Price
Organism
Human
Product Type
2D Cell
Tissue
Disease

Applications

Cosmetic (Efficacy)

Brightening

Professor Lee Chang-seok Eulji University
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Advancing K-Beauty with Skin Organoids: A Next-Generation Platform for Non-Animal Testing and High-Precision Cosmetic Innovation

With the global rise of K-beauty, the cosmetics industry continues to grow steadily. Since the ban on animal testing for cosmetics in Korea in 2017, various alternative testing methods have...

Tomocube (Spatial)
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HT-X1: A Label-Free Imaging Breakthrough for Organoid-Based Disease Modeling and Drug Screening

Traditional microscopy methods often require fluorescent labeling to analyze cellular structures, which can be time-consuming and invasive. In contrast, our HT-X1 system allows for high-resolution visualization of cellular morphology without...

Seoul National University College of Medicine
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Pioneering Spatial Protein Analysis in Korea: Advancing Clinical Pathology with Lambda Biologics’ Support

Traditional protein analysis has primarily focused on quantifying expression levels within tissue samples. However, recent advances in spatial analysis techniques have shifted attention toward evaluating not only expression levels, but...

K Research Institute
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ODISEI-Gut Platform Reveals Immune-Boosting Potential of Kimchi-Derived Bacterial Strain

Among the many fermented foods we consume, kimchi is particularly known for containing a diverse range of lactic acid bacteria, which are believed to influence the activation of immune cells...

Bundang Jesaeng General Hospital
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Multiplex Marker Analysis Enhances Research Efficiency with 31-Marker Detection on a Single Slide

We conducted a study focused on identifying disease-related markers using patient-derived tissue samples. However, traditional methods limited our ability to analyze multiple candidate markers simultaneously, and the limited availability of...

Description

Table of Contents

Skin brightening

The skin brightening efficacy test is a thorough evaluation process designed to measure the effectiveness of skincare products in enhancing skin radiance.
It involves baseline assessments, consistent product application, and data collection using advanced analysis tools.

Assay process

Step 1_1: After culturing the cell line, it undergoes a stabilization process.
Step 1_2: Identify the concentration range for sample toxicity and establish the test concentration.
Step 2_1: Stabilize the cells by culturing them in a 48-well plate for approximately 1 day.
Step 2_2: After verifying the condition of the stabilized cells, treat them with the melanin production-stimulating hormone (a-MSH), either alone or simultaneously with the sample.
Step 2_3: Assess the whitening efficacy by comparing the amount of melanin production in the group treated with a-MSH alone and the group treated simultaneously with the sample
Step 3_1: Confirmation through repeated experiments, spanning from the initial cell seeding to the formation of melanin.
Step 3_2: Arranging raw data and generating quantitative or morphology data.

Read Out

B16 cells
1. Microscopy data (cell morphology)
2. Extracellular melanin content (%) data
3. Intracellualr melanin content (%) data
Stimulation
1. General screening stimulus: a-MSH (B16 cell line)
2. In a light-induced melanin production model, the stimulus source can be replaceable with UVB
3. Efficacy screening is feasible without irritants when utilizing cell lines other than the B16 cell line (high reproducibility).
Cell line
1. Murine melanoma cell line : B16F10 , Melan-A
2. Human melanoma cell lin : MNT-1
3. Primary human melanocytes

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