Cancer Organoid

Hepatocarcinoma Cancer Organoid

Precise Tumor Environment Replication
Our Hepatocarcinoma Cancer Organoid model accurately simulates the patient's tumor in a 3D environment, ensuring precise research outcomes.
Personalized Treatment Development
Utilize our model to develop personalized treatments tailored to the unique genetic and cancer characteristics of each patient.
Innovative Drug Development
Boost drug development success with our model, saving time and costs by using actual tumor tissues for accurate predictions.


Price	1784€+ Login to see price
Organism	Human
Product Type	Organoid
Tissue	Hepatocellular carcinoma, Total necrotic lesion
Disease	Hepatocellular carcinoma

Applications

Oncology

Small Molecule

Antibody

Cancer Vaccine

mRNA

Immune Cell

TME-CAF

Immuno Oncology

Macrophage

Regulatory T Cell

Tumor-Infiltrating Lymphocyte

Cytotoxic T Cell

Description

Advancing Personalized Cancer Treatment with Hepatocellular Carcinoma Organoids

The hepatocellular carcinoma (HCC) organoids we create exhibit the same marker expression patterns, such as AFP positivity, CK19 negativity, and HepPar1 positivity, as the patient tissues they are derived from.
These organoids can be utilized for personalized drug testing, disease modeling, and biomarker discovery, ensuring that therapeutic strategies are tailored to the specific characteristics of each patient’s tumor.
We provide a valuable platform for developing and testing targeted therapies and studying tumor microenvironment interactions.

Hepatocarcinoma cancer organoid

Reliable Expression Analysis of Organoids Mirroring Tissue Samples

	H&E	AFP	CK19	EpCAM	HepPar 1
Cancer tissue
Cancer organoid

Our histological analysis demonstrated that the organoids faithfully replicated the expression patterns of critical markers AFP, CK19, EpCAM, and HepPar1 found in the original tissues.
This alignment proves the efficacy of our organoids for precise disease modeling and medical research, paving the way for targeted therapeutic applications and biomarker discovery.

Genetic mutation

Performing WES analysis on 7 hepatocarcinoma (hHCC) samples, the top 28 gene mutations were noticeably present across the samples, indicating a high level of mutation.
According to these results, conducting experiments using the various types of hepatocarcinoma samples we possess will likely yield results similar to those observed in actual human cases.