Adenoid (nasopharyngeal tonsil)-derived epithelial organoids preserve the cellular composition and
microscopic structures of adenoid tissue.
These organoids offer versatile applications, serving as valuable models for immune responses, infections, and disease studies.
They enable manipulation of disease pathways and facilitate drug testing.
Similar to tonsil organoids, adenoid organoids provide a scalable and reproducible method for in vitro research.
Adenoid organoid
As a virus-infected model, the
utilization of tonsil, adenoid, and lung organoids allows for the evaluation of antiviral drug efficacy and facilitates virus research.
Cell Type
· ASC
Assay
· SARS-COV-2 infection model
Confirmation of similarities between the characteristics of the tonsil and organoids through histological methods such as H&E staining, Alcian blue, PAS staining, and Masson’s trichrome.
Verification of the presence of adenoid epithelial markers, including NGFR, MUC1, E-cadherin, acetyl alpha tub, and Ki67, in organoids using IF/IHC, similar to their expression in the tissue.
