Highly multiplexed spatial transcriptomics in bacteria
Journal: Science
Author: Ari Sarfatis et al., USA
This study developed bacterial-MERFISH, a new method that combines microscopic expansion of bacterial cells with advanced imaging to study gene activity in individual bacteria. This breakthrough allows researchers to observe how bacteria behave in their natural environments and adapt to changes, offering insights into bacterial survival and interaction.
Deciphering the Influence of Effective Shear Modulus on Neuronal Network Directionality and Growth Cones’ Morphology via Laser-Assisted 3D-Printed Nanostructured Arrays
Journal: Advanced Functional Materials
Author: George Flamourakis et al., The Netherlands
Scientists investigated how 3D-printed nanopillar arrays influence neuronal growth in living cells. Their research demonstrates that different pillar heights significantly affect neuron development, network formation, and cell differentiation. This advances our understanding of brain cell mechanics and development.
Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy
Journal: Nature Communications
Author: A. Contreras-Sanz et al., Canada
Researches have developed an advanced method to analyze proteins in bladder cancer tissues before and after chemotherapy treatment. Their research identifies distinct protein patterns that can predict treatment response and patient survival, offering new insights for personalized cancer treatment strategies.
Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
Journal: Cell Reports
Author: Ali Khadim et al., Germany
This article discovers that during lung repair following injury, certain cells behave similarly to those found during early lung development. Their research shows that these specialized repair cells, called AMF-like cells, help rebuild damaged lung tissue. This finding provides new insights into how lungs heal and could lead to better treatments for lung diseases.
