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Latest Research Trends (9 Jan 2025)

Latest Research Trends (9 Jan 2025)

2024: research in review

Journal: Nature Biotechnology

A review of 2024’s significant biotechnological advancements, highlighting key research breakthroughs.

The article provides an overview of notable biotechnological developments in 2024, including the creation of glucose-responsive insulin, advancements in MHC I-binding systems for targeted peptide antigens, and innovations in optical perturbation screening methods.

Integrating bioelectronics with cell-based synthetic biology

Journal: Nature Reviews Bioengineering

Author: Jonathan Rivnay et. al , USA

Review explores synergy between engineered cells and bioelectronics for next-generation therapeutic applications.

Comprehensive review of cell-bioelectronics integration highlighting potential for regulated cell therapies and diagnostics, emphasizing closed-loop control systems and biohybrid devices.

Intratumor heterogeneity of EGFR expression

Journal: Nature Communications

Author: Bassel Alsaed et. al, Finland

Study reveals how EGFR expression variation influences drug resistance in lung cancer.

Research identifies how low-EGFR expressing cancer cells contribute to drug resistance and tumor microenvironment modification, suggesting new combination therapy approaches.

Endothelial-secreted Endocan activates PDGFRA

Journal: Nature Communications

Author: Soniya Bastola et al., USA

Study reveals Endocan’s role in glioblastoma progression through PDGFRA activation.

Investigation shows how endothelial-secreted Endocan influences glioblastoma behavior through PDGFRA signaling, affecting tumor growth and treatment resistance.

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