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Price | 5146€+ Login to see price |
Organism | Human |
Product Type | iPSC |
Tissue | Kreatinocytes, Urine, Blood, PBMCs |
Disease | – |
Applications
Toxicity
Organoid Based
Induced pluripotent stem cells (iPSCs) are created by reprogramming somatic cells to gain pluripotency, allowing them to differentiate into any cell type in the body.
This capability is crucial for studying cellular functions, creating disease models, and developing patient-specific therapies.
We utilize a variety of cells, including PBMC (peripheral blood mononuclear cells) and fibroblasts, to produce iPSCs.
Notably, our iPSC production method employs a non-integrating approach, ensuring both safety and efficiency.
By generating iPSCs without genetic modification, we obtain more natural and stable stem cells.
We rigorously check the presence of key pluripotency markers via flow cytometry and immunocytochemistry (ICC) to ensure that iPSCs remain undifferentiated until needed for your specific research purposes.
Verifying the true pluripotency of iPSCs (induced pluripotent stem cells) is a critical step in research.
The confirmation of trilineage differentiation involves assessing the ability of iPSCs to differentiate into the three germ layers: endoderm, mesoderm, and ectoderm.
This evaluation is conducted through teratoma formation and spontaneous differentiation into the three germ layers.
To guarantee safety of our cell cultures, we perform thorough mycoplasma contamination testing.
This ensures that our iPSCs are free from contaminants that could compromise your research.
We confirm the removal of reprogramming vectors to prevent any residual vector sequences from affecting the iPSCs
STR analysis is used to confirm that the original somatic cells and the reprogrammed iPSCs share the same genetic profile.
This ensures that the cells have been correctly reprogrammed.
Through karyotype analysis, it was confirmed that there were no chromosomal mutations in the iPSCs produced.
@ 2024 . All rights reserved
@ 2024 . All rights reserved
