Oncology
Immuno Oncology
Anti-Virus
Disease Modeling
Cosmetics
Toxicity
Spatial Biology
Technology Service
Cancer Organoid
Research Service
Others
Organism | |
Product Type | Organoid |
Tissue | PSC, Intestinal tissue |
Disease |
Applications
Inflammatory bowel disease (3D)
Inflammatory Bowel Disease (IBD) refers to a chronic condition characterized by inflammation within the gastrointestinal tract, causing inflammation of the intestinal walls.
Intestinal fibrosis model (3D)
Lambda's Intestinal Fibrosis Model addresses these challenges by leveraging high mimetic human intestinal organoids to create a model of inflammatory bowel diseases.
Probiotic adhesion assay (2D)
Lambda provides a 2D platform for gut attachment and allows for the evaluation of probiotics efficacy through gut attachment analysis.
Host-Microbiome study (3D)
Lambda's highly human-mimicking intestinal organoids enable realistic research on the gastrointestinal system and interactions between cells and microorganisms, serving as a versatile tool for drug development and disease research.
Drug absorption assay(2D)
Lambda provides drug absorption evaluation through drug (sample) permeability analysis using hPSC-derived human functional intestinal epithelial cells (hIEC).
We have developed highly functional organoids capable of long-term culture by applying our maturation technology to human intestinal organoids (hIO) derived from iPSCs.
Our intestinal organoids arecomposed of cells that resemble those of a mature human intestine.
Immunofluorescent staining with a proliferation marker (Ki-67), an epithelial marker (ECAD) and mature intestinal markers (DEFA5, OLFM4, MUC13, and KRT20).
Previous hIO
Mature hIO
Glucose-induced Ca2+ transients in real-time manner.
Mean values of peak fluorescence intensity by using Fluo-4-AM calcium indicator.
Representative images of the morphological changes after treatment with forskolin.
@ 2024 . All rights reserved
@ 2024 . All rights reserved
