Organoid Service

Gastric

3500€+
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Gastric

  • Replicate the complex cellular composition of the human liver, enabling in-depth studies on liver biology and function.
  • Allow for the modeling of liver diseases such as hepatitis and fibrosis, contributing to the understanding of disease mechanisms and the development of therapeutic strategies.
  • Mimic human liver metabolism, making it useful for studying drug metabolism, toxicity, and the development of personalized medicines.

Price
3500€+
Organism
Human
Product Type
iPS-derived organoid
Tissue
Gastric
Disease

Applications

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Autotelic bio
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As an expert with 20 years of experience in novel drug development, I firmly believe that tumor organoids are an innovative technology enabling accurate evaluation by comparing patient-derived cancer and...

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Colorectal cancer, unlike other cancer types, is significantly influenced by dietary and lifestyle factors. Evaluating drug responsiveness based on specific genetic markers and MSI (microsatellite instability) in patients is crucial,...

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Our NK immune cell-based cancer therapy faced challenges during its development and efficacy evaluation. To address these issues, we explored various platforms and discovered the Lambda Biologics platform, which we...

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The Organisation for Economic Co-operation and Development | OECD
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Enabling Global Drug Development: Lambda Biologics’ GLP-Validated, Organoid-Based Testing Platform

LambdaBiologics provides OECD-guideline-based testing services verified under GLP standards through its innovative research platform and diverse preclinical solutions. The company ensures optimal cost efficiency and performance for its clients, supporting...

Description

Generation process of human gastric organoid

Leveraging advancements in stem cell technology, we are pioneers in developing human gastric organoids derived from both tissue samples and induced pluripotent stem cells (iPSCs). Our state-of-the-art techniques facilitate precise gastric differentiation from iPSCs, enabling the creation of highly functional and physiologically relevant gastric organoids. These organoids are invaluable tools for experimental research and therapeutic innovation.

Generation of Gastric organoids

Cellular and structural similarity

Generation of Gastric organoids

Our gastric organoids closely mimic the key structural features of human stomach tissue, replicating the morphology of the gastric epithelium, including critical structures like gastric glands. They are composed of various cell types, including parietal cells, chief cells, mucous cells, and enteroendocrine cells, accurately reflecting the functional complexity of real gastric tissue.

Expression markers
  • β-catenin​ Stem/Proliferative Cells
  • SOX2 Stem and Progenitor Cells
  • ECAD Epithelial Cells

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