Cancer Organoid

Endometrial Cancer Organoid

Endometrial cancer organoids are three-dimensional (3D) models that closely replicate the structure and cellular composition of actual cancer tissue.
By preserving key characteristics of endometrial cancer, including genetic mutations and protein expression patterns, these organoids serve as reliable models for cancer research.
Their ability to maintain tumor heterogeneity and accurately mimic the tumor microenvironment (TME) makes them invaluable for studying disease progression and treatment responses.
As physiologically relevant models, endometrial cancer organoids play a crucial role in advancing precision medicine and facilitating the development of more effective cancer therapies.


Price	1784€+ Login to see price
Organism	Human
Product Type	Tissue derived organoid
Tissue	Endometrium
Disease	Endometrial cancer

Applications

Toxicity

Small molecules

mRNA

Antibody

Cancer vaccine

Immune Cells

Immuno Oncology with TME

Cytotoxic T cell

TIL (Tumor infiltrating lymphocytes)

Regulatory T cell

Macrophage

CAF (Cancer associate fibroblast)

Description

Cellular and structural similarity

Our endometrial cancer (EC) organoids exhibit a high degree of pathological similarity to patient-derived tumor tissues, expressing key endometrial cancer markers such as Vimentin (VIM), estrogen receptor (ER), and progesterone receptor (PR). Immunofluorescence (IF) analyses confirm that these markers are expressed in the organoids in patterns consistent with those observed in primary tumors, accurately reflecting the differentiation status and histological characteristics of the original tissue.

These pathological marker analyses demonstrate that endometrial cancer organoids faithfully recapitulate the morphological and molecular features of patient tumors, establishing them as a reliable platform for cancer pathology research, drug development, and the evaluation of personalized therapeutic strategies.