Accurately detect early cytotoxic effects through label-free 3D live-cell imaging. Holotomography enables single-cell-level differentiation of viable, stressed, and dying cells while preserving native cellular behavior.
Price | 1000€+ |
Organism | – |
Product Type | – |
Tissue | – |
Disease | – |
Applications
Holotomography
Cell biology
With the global rise of K-beauty, the cosmetics industry continues to grow steadily. Since the ban on animal testing for cosmetics in Korea in 2017, various alternative testing methods have...
Traditional microscopy methods often require fluorescent labeling to analyze cellular structures, which can be time-consuming and invasive. In contrast, our HT-X1 system allows for high-resolution visualization of cellular morphology without...
Traditional protein analysis has primarily focused on quantifying expression levels within tissue samples. However, recent advances in spatial analysis techniques have shifted attention toward evaluating not only expression levels, but...
We conducted a study focused on identifying disease-related markers using patient-derived tissue samples. However, traditional methods limited our ability to analyze multiple candidate markers simultaneously, and the limited availability of...
Accurate cytotoxicity assessment is a critical step in drug discovery, safety evaluation, and disease modeling. However, conventional cytotoxicity assays often rely on fluorescent labels or chemical staining, which can perturb cellular physiology, limit long-term observation, and obscure early-stage cellular stress responses.
Lambda Biologics offers a label-free 3D cytotoxicity assay using Holotomography (HT), enabling real-time, quantitative analysis of live cells without altering their native behavior. By capturing high-resolution, three-dimensional refractive index maps, this approach reveals subtle morphological and biophysical changes that precede irreversible cell death—changes that are often missed by endpoint or dye-based assays.
With Holotomography-based cytotoxicity analysis, researchers can differentiate viable, stressed, and dying cells at single-cell resolution, monitor apoptosis and necrosis pathways over time, and generate reproducible, publication-ready data for drug screening and toxicity studies. This non-invasive platform supports early toxicity detection while remaining compatible with animal-free, NAM-compliant research workflows.
Holotomography (HT) enables 3D visualization of live cells without fluorescent labels or chemical staining, preserving native cellular behavior during cytotoxicity assays. This approach allows researchers to:
