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Price | 2388€+ Login to see price |
Organism | Human |
Product Type | Organoid |
Tissue | iPSC |
Disease | – |
Applications
Toxicity
Organoid Based
Disease Modeling
Brain & CNS Disease Model
We have developed highly functional organoids capable of long-term culture by applying our maturation technology to human brain organoids derived from hPSCs.
Our cerebral organoids can be observed in a structurally mature form. It mimics the multi-layered structure found in the actual human brain, and this organoid is composed of various cells such as neurons and glial cells.
In our brain organoids, electrical signals from nerve cells, characteristic of the human brain, were detected.
Through this, it was confirmed that it is a functionally mature organoid, and through long-term culture, the brain waves that appear in premature babies can also be confirmed.
We can generate organoid models of neurodegenerative diseases through two methods.
The first method is to differentiate induced pluripotent stem cells into brain organoids and create a disease model by producing GBM cells and assembloids.
The second method is to destroy or overexpress the gene to be identified in normal induced pluripotent stem cells, differentiate them into organoids, and then create a disease model.
We created brain tumor organoids using cells derived from patient brain tumor tissue.
It was confirmed that the tumor was suppressed by treating temozolomide, a well-known drug, using glioblastoma organoids. This can be used to discover new drugs.
@ 2024 . All rights reserved
@ 2024 . All rights reserved
