AF solution
Oncology
Immuno Oncology
Anti-Virus
Disease Modeling
Cosmetics
Toxicity
Spatial Biology
Technology Service
Cancer Organoid
Research Service
Others
Organism | |
Product Type | Organoid |
Tissue | iPSC |
Disease |
Applications
Neurodegenerative diseases (such as dementia)
Inflammatory Bowel Disease (IBD) refers to a chronic condition characterized by inflammation within the gastrointestinal tract, causing inflammation of the intestinal walls.
Brain tumors
Lambda's Intestinal Fibrosis Model addresses these challenges by leveraging high mimetic human intestinal organoids to create a model of inflammatory bowel diseases.
Neurodevelopmental disorders
Lambda provides a 2D platform for gut attachment and allows for the evaluation of probiotics efficacy through gut attachment analysis.
Neurotoxicity assessment
Lambda's highly human-mimicking intestinal organoids enable realistic research on the gastrointestinal system and interactions between cells and microorganisms, serving as a versatile tool for drug development and disease research.
Infectious Disease
As a virus-infected model, the utilization of tonsil, adenoid, and lung organoids allows for the evaluation of antiviral drug efficacy and facilitates virus research.
We have developed highly functional organoids capable of long-term culture by applying our maturation technology to human brain organoids derived from hPSCs.
Our cerebral organoids can be observed in a structurally mature form. It mimics the multi-layered structure found in the actual human brain, and this organoid is composed of various cells such as neurons and glial cells.
In our brain organoids, electrical signals from nerve cells, characteristic of the human brain, were detected.
Through this, it was confirmed that it is a functionally mature organoid, and through long-term culture, the brain waves that appear in premature babies can also be confirmed.
We can generate organoid models of neurodegenerative diseases through two methods.
The first method is to differentiate induced pluripotent stem cells into brain organoids and create a disease model by producing GBM cells and assembloids.
The second method is to destroy or overexpress the gene to be identified in normal induced pluripotent stem cells, differentiate them into organoids, and then create a disease model.
We created brain tumor organoids using cells derived from patient brain tumor tissue.
It was confirmed that the tumor was suppressed by treating temozolomide, a well-known drug, using glioblastoma organoids. This can be used to discover new drugs.
@ 2024 . All rights reserved
@ 2024 . All rights reserved
