Lambda offers a highly mimetic in vitro skin model for conducting various skin-related tests. We provide 11 efficacy testing services for skin, leveraging our advanced skin mimicry technology.
Eye irritation test is in accordance with the Ministry of Food and Drug Safety guidelines, assesses eye irritation potential using bovine corneas.
Eye irritation test - BCOP assay
To determine the eye irritation of a test substance, it is applied tothe cornea of a cow. The opacity (cloudiness) and permeability of the cornea are then measured. These measurements are used to calculate the OcularIrritation Index (IVIS), which is indicative of the test substance’s eye irritation potential. Based on the opacity and permeability measurements obtained from the corneal exposure test, the ocular irritation index (IVIS) is calculated. This index serves as a quantitative measure to evaluate the eye irritation potential of the test substance.
Starting cost
€0+
Assay process
Readout
BCOP Opacity
BCOP Permeability
BCOP In Vitro Irritancy Score (Opacity+15* Permeability)