To gauge the extent of drug absorption relevant to an actual person, organoids are utilized to measure the degree of drug absorption to ensure its usability.
Lambda provides drug absorption evaluation through drug (sample) permeability analysis using hPSC-derived human functional intestinal epithelial cells (hIEC).
Lambda provides drug absorption evaluation through drug (sample) permeability analysis using hPSC-derived human functional intestinal epithelial cells (hIEC).
Assay process
Technical
Comparison of predicted fraction absorbed by the human intestine of six model compounds in functional hIEC and Caco-2 cell system.
Functional hIECs can better predict the absorption and extent of oral bioavailability in humans.