Price | 2874€+ Login to see price |
Organism | Human |
Product Type | 2D Cell |
Tissue | – |
Disease | – |
Applications
Cosmetic (Efficacy)
Brightening
With the global rise of K-beauty, the cosmetics industry continues to grow steadily. Since the ban on animal testing for cosmetics in Korea in 2017, various alternative testing methods have...
Traditional microscopy methods often require fluorescent labeling to analyze cellular structures, which can be time-consuming and invasive. In contrast, our HT-X1 system allows for high-resolution visualization of cellular morphology without...
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We conducted a study focused on identifying disease-related markers using patient-derived tissue samples. However, traditional methods limited our ability to analyze multiple candidate markers simultaneously, and the limited availability of...
Targeted Melanin Studies
Utilize the Melan-A cell line to delve into melanin synthesis and regulation, critical for uncovering new pathways to reduce hyperpigmentation and enhance skin brightening.
Product Development and Testing
Use Melan-A cells to rigorously test the efficacy of skin brightening agents, ensuring they target and modulate melanin production effectively.
Safety and Compatibility Testing
Employ Melan-A cells to assess the safety and skin compatibility of new cosmetic products, making sure they are gentle yet effective for everyday use.
In-depth Melanoma Analysis
Utilize MNT-1 for detailed studies on melanoma mechanisms and therapeutic development.
Targeted Drug Testing
Leverage MNT-1 cells for precise evaluations of new treatments’ efficacy and safety.
Molecular Discovery
Explore genetic insights and potential targets with the MNT-1 melanoma cell line.
Pigmentation Insight
Utilize the B16F1 cell line to gain valuable insights into melanin production mechanisms, essential for developing effective skin brightening treatments.
Efficacy Testing
Leverage B16F1 cells to test and validate the effectiveness of brightening agents, ensuring they effectively reduce pigmentation and enhance skin luminosity.
Safety and Toxicity Assessments
Employ B16F1 cells to conduct thorough safety and toxicity evaluations of new skin care products, guaranteeing they are safe for consumer use while achieving desired brightening effects.
Enhanced Pigmentation Studies
Utilize our melanocyte services to explore pigmentation processes and disorders in-depth, providing crucial insights into skin health and cosmetic development.
Tailored Cosmetic Testing
Assess the efficacy of skincare products on real human melanocytes, ensuring safety and effectiveness tailored to diverse skin types.
Advanced Disease Modeling
Leverage our melanocytes to model skin conditions such as vitiligo and hyperpigmentation, accelerating the discovery of targeted treatments.
The skin brightening efficacy test is a thorough evaluation process designed to measure the effectiveness of skincare products in enhancing skin radiance.
It involves baseline assessments, consistent product application, and data collection using advanced analysis tools.
1. Microscopy data (cell morphology)
2. Extracellular melanin content (%) data
3. Intracellualr melanin content (%) data
1. After culturing the cell line, it undergoes a stabilization process.
2. Identify the concentration range for sample toxicity and establish the test concentration.
1. Stabilize the cells by culturing them in a 48-well plate for approximately 1 day.
2. After verifying the condition of the stabilized cells, treat them with the melanin production-stimulating hormone (a-MSH), either alone or simultaneously with the sample.
3. Assess the whitening efficacy by comparing the amount of melanin production in the group treated with a-MSH alone and the group treated simultaneously with the sample
1. Confirmation through repeated experiments, spanning from the initial cell seeding to the formation of melanin.
2. Arranging raw data and generating quantitative or morphology data.
General screening stimulus: a-MSH (B16 cell line)
In a light-induced melanin production model, the stimulus source can be replaceable with UVB
Efficacy screening is feasible without irritants when utilizing cell lines other than the B16 cell line (high reproducibility).
1. Murine melanoma cell line : B16F10 , Melan-A
2. Human melanoma cell lin : MNT-1
3. Primary human melanocytes
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info@lambdabiologics.com