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Service Type

Holotomography

Cell Biology

3D Biology

Immunology

LLPS

Service Type

Holotomography

Experience a revolution in cell imaging services with Lambda AF Solutions’ holotomography technology.

Holotomography (HT) is an advanced imaging technique that uses low-power visible light to illuminate cells from various angles and measures the phase delay of the transmitted light.
Unlike CT, HT uses the refractive index (RI) to provide imaging contrast, allowing the visualization of living cells and tissues without the need for labeling or staining.
This service is offered in a CRO format, supporting clients’ research by enabling more precise cell imaging.

Application

Holotomography

3D biology

Holotomography

Immunology

Holotomography

LLPS

Description

Holotomography

Label-free live cell imaging

Holotomography (HT) imaging eliminates the need for labeling or dyeing, therefore minimizing artificial manipulation effects and simplifying sample preparation. This approach allows the observation of samples in their natural state, providing more reliable and relevant information.

High-resolution 3D imaging

HT provides high-content, high-resolution, three-dimensional images, allowing researchers to capture detailed information about cellular structures. This high level of detail is crucial for studying cellular morphology and dynamics.

Long-term timelapse imaging

HT facilitates continuous monitoring of cellular phenomena over extended time frames. This feature is beneficial for studying processes that unfold over hours, days, or even weeks, providing a comprehensive understanding of long-term cellular behavior.

Quantitative analysis

HT allows for quantitative analysis of cellular parameters. It can measure physical quantities such as mean refractive index,dry mass, and concentration, as well as various shape measurements like area, length, volume, and surface area.

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