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OPAL

Adaptive Spatial Profiling Solution

Starting cost
€ 0 +

€15.380+

CODEX

€4.480+

OPAL

Visium

€8.200+

Preparing

GeoMX

€10.890+

Preparing

Hyperion

€3.200+

Request a quote

OPAL

OPAL has the advantage of being able to stain freely without restrictions on the host of the primary antibody, making it easy to use antibodies already available in the laboratory and increasing experimental flexibility.

It is possible to stain up to 8 biomarkers at a time, and has the advantage of being relatively cheaper than CODEX staining.

OPAL

  • 6 marker staining capabilities on a single tissue slide.
  • High compatibility with existing IHC and freedom to choose biomarkers.
  • Construction of organoid-optimized panels for tissue-level analysis.
  • Solutions optimized for diagnostic marker testing.
  • Rapid cellular phenotyping and neighborhood analysis.

Process

Staining

2 days

  • FFPE or FF tissue section
  • Antigen Unmaking
  • Tissue staining
  • Primary antibody incubation
  • Reporter plate preparation
  • PCF run

Image

1-3 days per slide

  • Continuous speed improvements
  • Workflow simplification
  • Consistent imaging methods

Analyze

4 months

  • Proprietary data compression
  • Solutions serve every user need
  • Consistent image analysis methods
  • Step. 1 : Sample preparation
  • Step. 2 : Tissue staining (primary antibody & fluorophore)
  • Step. 3 : PIF run
  • Step. 4 : Data analysis

Readout

Liver organoid

H&E

OPAL

Merge

DAPI

ALB

ALB

PDGFR

BSEP

COL1

CD31

Brain organoid

H&E

OPAL

Merge

DAPI

NeuN

NF-M

MAP2

GFAP

SOX2

NG2

Colon organoid

H&E

OPAL

Merge

DAPI

ChaA

ECAD

SOX9

Lyz

Muc2

SI

Confirmation of similarity using OPAL staining in organoids derived from various organs undergoing differentiation.

OPAL

Merge

DAPI

OLFM4

SLC26A3

MUC2

FCGBP

KRT20

TMM40

Outcomes of organoid and co-culture cell analysis through OPAL staining

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AF Solution

Resources

Lambda

BioArt

Lambda Biologics

Lambda Biologics

Contact

+49 (0) 152 293 76591

info@lambdabiologics.com​

Deutscher Pl. 5c

04103 Leipzig

Germany

@ 2024 . All rights reserved

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Deutscher Pl. 5c

04103 Leipzig

Germany

@ 2024 . All rights reserved

Privacy Policy
Term of Services
Cookie Settings